Personalized Genomic Skincare

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AXESOME is a pioneering academic think tank implementing the personalized genomic approach in skincare.

It is a biotechnology company dedicated to the compound application of pure and licensed skincare vesicles derived from multiple natural sources.

AXESOME is a pioneering academic think tank implementing the personalized genomic approach in skincare.

It is a biotechnology company dedicated to the compound application of pure and licensed skincare vesicles derived from multiple natural sources.

 

Compound Exosome Stimulators

Why 'Compound Products'?

Today, exosome science is recognized as one of the most cutting-edge biotechnological approaches in the fields of cellular regeneration and vesicular communication.
However, a single exosome source may be insufficient to meet all the biological needs of the skin. Therefore, AXESOME employs a compound (multi-source) structure composed of a combination of botanical, animal, and biomimetic sources.

Botanical Sources

They offer the advantages of potent antioxidant content, richness in phenolic compounds, and high biocompatibility. However, their membrane stability is weak, and tissue penetration is limited.

Animal Sources

They are rich in cellular growth factors and lipid structures, and are effective in dermal regeneration. However, their immunogenic risks must be carefully managed.

Biomimetic Vesicular Phospholipid Structures

These are pure and stable structures manufactured under GMP conditions. They possess high stability; however, production costs are high, and their effects are limited to miRNA stimulation signals.

When viewed from the perspective of ‘signal transduction’ influencing cell differentiation, a ‘smart product formulation’ is required—one capable of targeting all six main sub-pathways of membrane transport.

For perfect efficacy, a multi-faceted alliance and a harmonious synergy that address all pathways are essential.

Thus, we can combine the power of botanicals for ‘skin moisture balance and oxidative stress,’ milk and colostrum for ‘regeneration and immunomodulation,’ and biomimetics for ‘telomere repair and anti-pigmentation.’

Personalized Genomic Skincare

What lies beyond the ‘Most Potent and Comprehensive Compound Product Cocktail’?

The Answer:

Individualized Dermatology.

A blend tailored to your genome.

Why Personalized Care?

  • It is more targeted and responsive.
  • It ensures a more cost-effective and rational skincare regimen in the long run.
  • It addresses the specific needs of the genome and prevents investment in unnecessary elements.

How Can ‘Compound Products’ Be Utilized via the Approach of Individualized Dermatology?

Personalized genomic skincare aims to customize care strategies based on the individual’s profile by characterizing skin biology at the transcriptomic level.
The foundation of this approach relies on mapping the total RNA derived from skin cells via the Total RNA Sequencing method.

The sequencing test quantitatively determines the genes actively expressed in the cell, suppressed pathways, and all regulatory RNA profiles. In this way, the individual-specific activity levels of processes such as collagen synthesis, inflammation, oxidative stress, or melanin production are revealed.

The resulting total RNA map reflects each individual’s unique biological signature in terms of skin aging rate, regeneration capacity, and cellular stress response. These data are used in the design of personalized formulations targeting specific gene pathways, enabling the development of ‘biologically smart’ skincare products that go beyond conventional cosmetics.